Natural and induced blood dissemination of Toxoplasma gondii: experimental model in white mice and hamsters
Rev. biol. trop
; 41(2): 197-202, ago. 1993. tab, graf
Article
in En
| LILACS
| ID: lil-148877
Responsible library:
BR1.1
RESUMO
Blood inoculation in mice showed that Toxoplasma organisms circulate in blood after 1 h of oocyst infection. Parasites were detected up to 15 days later and then disappeared from the bloodstream concomitantly with cyst formation in the brain, probably due to antibody presence. Immunosuppression caused by cortisone acetate treatment induced Toxoplasma bloodstream invasion in chronically infected mice and hamsters, causing death in some. Natural dissemination is discussed in relation with congenital toxoplasmosis. Induced immunosuppressive effect is compared with that produced by natural diseases such as Hodgkin, lymphoma, AIDS and others
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Index:
LILACS
Main subject:
Toxoplasma
/
Toxoplasmosis, Animal
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
Rev. biol. trop
Journal subject:
BIOLOGIA
/
MEDICINA TROPICAL
Year:
1993
Type:
Article