Synaptophysin and neurofilament expression in neurons infected with dengue virus
Arch. med. res
; 25(2): 215-7, 1994. ilus
Article
in En
| LILACS
| ID: lil-198810
Responsible library:
MX1.1
ABSTRACT
The expression of two genes encoding the neuronal specific proteins synaptophysin and high molecular weigh neurofilaments was investigated in primary cell cultures of embryonic mouse brain infected with dengue virus type 2, using immunocytochemistry and Western blot analysis with monoclonal antibodies. The viral infection leads to a 20-fold induction in the expression of the mentioned synaptogenesis-related proteins. These results suggest a correlation between virus infection and neuropathology of immature neurons in vivo
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Index:
LILACS
Main subject:
Synapses
/
Intermediate Filaments
/
Blotting, Western
/
Dengue Virus
/
Flavivirus
/
Neurons
Limits:
Animals
Language:
En
Journal:
Arch. med. res
Journal subject:
MEDICINA
Year:
1994
Type:
Article