The hematopoietic stroma
Braz. j. med. biol. res
; 32(5): 601-9, May 1999.
Article
in En
| LILACS
| ID: lil-233478
Responsible library:
BR1.1
RESUMO
All blood cells are derived from a small common pool of totipotent cells, called hematopoietic stem cells. The process is strictly regulated by the hematopoietic microenvironment, which includes stromal cells, extracellular matrix molecules and soluble regulatory factors. Several experimental in vitro assays have been developed for the study of hematopoietic differentiation, and have provided valuable information on the stroma, which includes, among other cell types, macrophages, fibroblasts, adipocytes, and endothelial cells. The composition, ontogeny, and function in physiological as well as pathological conditions of stroma are discussed
Full text:
1
Index:
LILACS
Main subject:
Hematopoietic Stem Cells
/
Hematopoiesis
Limits:
Humans
Language:
En
Journal:
Braz. j. med. biol. res
Journal subject:
BIOLOGIA
/
MEDICINA
Year:
1999
Type:
Article
/
Congress and conference