Emergencia de resistencia a macrólidos en streptococcus pyogenes / Emergence of macrolide resistant streptococcus pyogenes strains
Rev. méd. Chile
; 127(12): 1447-52, dic. 1999. tab
Article
in Es
| LILACS
| ID: lil-258068
Responsible library:
CL1.1
RESUMO
Background:
Diseases produced by Streptoccocus pyogenes are still a problem in Chile, as in the rest of the world. It exhibits in vitro susceptibility to different antimicrobials, but penicillin continues to be the treatment of choice. Alternative drugs have been developed for allergic patients, such as erythromycin, new macrolides and cephalosporins. Nevertheless, resistant strains are appearing due to the indiscriminate use of macrolides.Aim:
To assess present antimicrobial susceptibility of S Pyogenes strains isolated from chilean patients. Material andMethods:
The susceptibility to penicillin, macrolides, clindamycin, cephalotin and vancomycin of 153 S Pyogenes strains, obtained from different health centers of the Metropolitan Region and isolated between 1996 and 1998, was assessed using the Kirby-Bauer method. Agar dilution minimal inhibitory concentration was then determined to macrolide resistant strains.Results:
All strains were susceptible to penicillin. There was a 7.2 percent cross-resistance to macrolides.Conclusions:
These results confirm that S Pyogenes resistance to macrolides has increased considerably in the Metropolitan Region of Chile during the last years
Full text:
1
Index:
LILACS
Main subject:
Streptococcus pyogenes
/
In Vitro Techniques
/
Anti-Bacterial Agents
Language:
Es
Journal:
Rev. méd. Chile
Journal subject:
MEDICINA
Year:
1999
Type:
Article