Incidence of Gardnerella vaginalis, Candida sp and human papilloma virus in cytological smears
São Paulo med. j
;
118(4): 105-8, July 2000. tab
Article
in English
| LILACS
| ID: lil-264471
ABSTRACT
CONTEXT In spite of the wide-ranging literature on the microbiology of normal and abnormal flora of the vagina, there are few studies on the relationship between human papilloma virus (HPV) and other vaginal microorganisms. OBJECTIVE:
To analyze the frequency of infection by human papilloma virus (HPV) and other agents like Candida sp., Gardnerella vaginalis and Trichomonas vaginalis in cytological smears. DESIGN STUDY Retrospective studySETTING:
A public tertiary referral center. SAMPLE An analysis of 17,391 cytologies from outpatients seen between January 1997 and August 1998. The control group was made up of patients in the same age group and same period with no cytological evidence of HPV infection. Patients with a diagnosis of cervical intraepithelial neoplasia (CIN) II or III were excluded from this analysis. MAIN MEASUREMENTS The diagnosis of HPV infection was made in accordance with the criteria of Schneider et al. and the diagnosis of Gardnerella vaginalis was made with a finding of clue cells.RESULTS:
390 (2.24 per cent) had alterations consistent with infection by HPV, sometimes associated with CIN I. The results showed that Gardnerella vaginalis was the most frequent agent in women with HPV infection (23.6 per cent versus 17.4 per cent; P <0.05), while in the control group the most frequent agent was Candida sp. (23.9 per cent versus 13.8 per cent; p <0.001).CONCLUSION:
In spite of this study being based solely on cytological criteria, in which specific HPV and Gardnerella diagnostic tests were not used, the cytological smear is widely used in clinical practice and the data presented in this investigation show that there is an association between Gardnerella vaginalis and HPV infection. It remains to be established whether the microorganisms favor each other
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Trichomonas Vaginitis
/
Tumor Virus Infections
/
Vaginal Smears
/
Candidiasis
/
Vaginosis, Bacterial
/
Papillomavirus Infections
Type of study:
Incidence study
/
Observational study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicine
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
2000
Type:
Article
Affiliation country:
Brazil
Similar
MEDLINE
...
LILACS
LIS