Vanishing bile duct syndrome in Hodgkin's disease: case report
São Paulo med. j
; São Paulo med. j;118(5): 154-7, Sept. 2000.
Article
in En
| LILACS
| ID: lil-271290
Responsible library:
BR1.1
ABSTRACT
CONTEXT Liver damage is relatively common in patients affected by Hodgkin's disease. A smaller proportion of cases develops jaundice. Recently, the vanishing bile duct syndrome was described in Hodgkin's disease. The mechanisms of this severe complication have been poorly understood until now. OBJECTIVE:
To describe a rare case of intra-hepatic cholestasis due to vanishing bile duct syndrome.DESIGN:
Case report. CASE REPORT A 38-year-old male patient affected by Hodgkin's disease. Liver biopsy showed no detectable Hodgkin's disease. Intra-hepatic cholestasis was found and none of the six portal tracts analyzed contained normal bile ducts. The treatment was based on conventional and high-dose escalation chemotherapy. The patient died from an irreversible liver failure while in complete remission from Hodgkin's disease
Full text:
1
Index:
LILACS
Main subject:
Hodgkin Disease
/
Common Bile Duct Diseases
Type of study:
Etiology_studies
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
Sao Paulo Med J
/
São Paulo med. j
/
São Paulo med. j. (Online)
/
São Paulo medical journal (Impresso)
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
MEDICINA
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
2000
Type:
Article