The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis
Braz. j. med. biol. res
;
34(2): 145-154, Feb. 2001.
Article
in English
| LILACS
| ID: lil-281592
ABSTRACT
This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether panic is a very intense anxiety or something else, and what aspects of clinical anxiety are reproduced by animal models. Concerning the first issue, most participants agreed that generalized anxiety and panic disorder are different on the basis of clinical manifestations, drug response and animal models. Also, underlying brain structures, neurotransmitter modulation and hormonal changes seem to involve important differences. It is also common knowledge that existing animal models generate different types of fear/anxiety. A challenge for future research is to establish a good correlation between animal models and nosological classification
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Anxiety
/
Panic
/
Disease Models, Animal
Limits:
Humans
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
2001
Type:
Article
Affiliation country:
Brazil
/
France
/
United States
/
United kingdom
Institution/Affiliation country:
Aston University/GB
/
Central Nervous System Research Department/FR
/
Hoffmann-La Roche Ltd./CH
/
Universidade Federal de Santa Catarina/BR
/
Universidade Federal de São Paulo/BR
/
Universidade Federal do Espírito Santo/BR
/
Universidade Federal do Paraná/BR
/
Universidade de São Paulo/BR
/
University of Hawaii/US
/
University of Leeds/GB
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