Evaluation of the performance of a novel ceramic membrane bioreactor using the fungus Penicillium chrysogenum
Braz. j. microbiol
;
31(supl.1): 61-6, Oct. 2000. ilus, graf
Article
in English
| LILACS
| ID: lil-300569
RESUMO
The fungus Penicillium chrysogenum IFO-8644 was grown in a new type of ceramic membrane bioreactor operating with synthetic and complex germination medium at 27§C and pH7.0, using membranes with average pore diameters of 2.28 mm and effective area of 26.5 cm². Tests with different age inocula, an important factor in the development of the microorganisms, were performed. The best results were obtained using fresh inocula. Another extremely important factor to be considered in the desing of the bioreactor was the available membrane area for the growth of the fungus. As to the metabolism, sucrose was confirmed as the best source of carbon and energy since glucose had a repressive effect on the antibiotic production. A mathematical model, based on Monod growth kinetics for cell inhibition, enabled a reliable representation of the behavior of the bioreactor. Analysis of the experimental and simulated results showed that the bioprecess is viable in the novel bioreactor and that this bioreactor presents very promising potentials for large scale use.
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Index:
LILACS (Americas)
Main subject:
Penicillium chrysogenum
/
In Vitro Techniques
/
Bioreactors
Type of study:
Prognostic study
Language:
English
Journal:
Braz. j. microbiol
Journal subject:
Microbiology
Year:
2000
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de São Carlos, São Carlos, SP. Depto. de Engenharia Química/BR
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