Presence of ductal carcinoma in situ confers an improved prognosis for patients with T1N0M0 invasive breast carcinoma
Braz. j. med. biol. res
;
35(8): 913-919, Aug. 2002. tab, graf
Article
in English
| LILACS
| ID: lil-325544
ABSTRACT
We have retrospectively analyzed a series of 155 sequential cases of T1N0M0 ductal carcinomas of which 51 tumors had a ductal carcinoma in situ (DCIS) component for correlation between the presence of DCIS and clinicopathological variables, recurrence and patient survival. No correlations between the presence of DCIS and age, menopausal status, size, estrogen or progesterone receptors were found. High-grade infiltrative tumors tended not to present a DCIS component (P = 0.08). Patients with tumors associated with DCIS form a subgroup with few recurrences (P = 0.003) and good survival (P = 0.008). When tumors were classified by size, an association between large tumors (>1.0 cm) and increased recurrence and shortened overall survival was found. The presence of DCIS in this subgroup significantly reduced the relative risk of death
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Breast Neoplasms
/
Carcinoma, Intraductal, Noninfiltrating
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
2002
Type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital do Câncer A.C. Camargo/BR
/
Instituto Ludwig de Pesquisa sobre o Câncer/BR
/
Universidade de Säo Paulo/BR
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