Prevalence of human herpesvirus 8 antibodies in the population of Belém, Pará, Brazil
Rev. Inst. Med. Trop. Säo Paulo
; 44(6): 309-313, Nov.-Dec. 2002. tab
Article
in En
| LILACS
| ID: lil-326348
Responsible library:
BR1.1
ABSTRACT
Serum samples from 497 children and adults inhabiting two neighbourhoods (Guamß and Terra Firme) in BelÚm, Parß, North Brazil were screened for the presence of human herpesvirus 8 (HHV-8) antibody using an enzyme-linked immunosorbent assay. An overall 16.3 percent prevalence was found for these urban communities. Taken both genders together, prevalence rates of HHV-8 antibody increase gradually, across age-groups, ranging from 12.0 percent to 33.3 percent. When seroprevalence is analysed by gender, similar rates are found for female (18.4 percent) and male (14.0 percent) individuals. In the former gender group, seroprevalence rates increased from 10.3 percent, in children FACE="Symbol">ú 10 years of age, to 30.0 percent in adults 41-50 years of age. Conversely, among male subjects, the prevalence of HHV-8 antibodies decreased from 13.3 percent in children/young adults aged FACE="Symbol">ú 10 to 20 years of age to 6.1 percent in adults aged 21-30 years. From the 31-40 year-old group male onwards, seropositivity rates increased gradually, ranging from 8.3 percent to 66.7 percent. A significant difference in seropositivity rates was noted when comparing 21-30 age groups for female and male subjects:
23.3 percent and 6.1 percent, respectively (P = 0.03). Geometric mean optical densities were found to increase slightly from the lower to the higher age-groups. Our data suggest that transmission of HHV-8 occurs frequently in the general urban population of BelÚm, and that prevalence of antibody seems to increase with age
Full text:
1
Index:
LILACS
Main subject:
Herpesviridae Infections
/
Herpesvirus 8, Human
/
Antibodies, Viral
Type of study:
Etiology_studies
/
Prevalence_studies
/
Prognostic_studies
/
Screening_studies
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Rev. Inst. Med. Trop. Säo Paulo
Journal subject:
MEDICINA TROPICAL
Year:
2002
Type:
Article