Streptococcus pneumoniae: evolución de la resistencia a los antimicrobianos en un hospital de niños de Córdoba, Argentina / Streptococcus pneumoniae: evolution of antibiotic resistance in a pediatric hospital in Córdoba, Argentina
Rev. argent. microbiol
; Rev. argent. microbiol;33(3): 149-154, jul.-sept. 2001.
Article
in Es
| LILACS
| ID: lil-332487
Responsible library:
BR1.1
RESUMO
The wide variety of prevalence of antimicrobial resistant Streptococcus pneumoniae in different countries confirms the importance of determining local patterns of resistance. From 1992 to 2000, we studied the pattern of antimicrobial resistance in S. pneumoniae and its evolution along the years, using 468 strains isolated in the Hospital de Niños de Córdoba. A total of 177 isolates (37.8) were not susceptible to penicillin, with 19 intermediate and 18.8 resistant strains. High and intermediate resistance levels to cefotaxime were 4.9 and 10.9, respectively. Decreased susceptibility to trimethoprim/sulfamethoxazole (TMS), erythromycin, chloramphenicol, and rifampin was found in 194 isolates (41.5), 32 (6.8), 13 (2.8) and 3 (0.6), respectively. No isolates resistant to vancomycin were detected. The most commonly combined resistance patterns were penicillin/TMS (35.6) and penicillin/TMS/cefotaxime (11.8). This study highlights the increased rate of drug resistant S. pneumoniae during the last years, and the importance of antimicrobial resistance surveillance of adequate empirical therapy involving local and regional susceptibility patterns.
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Index:
LILACS
Main subject:
Streptococcal Infections
/
Streptococcus pneumoniae
/
Drug Resistance, Microbial
/
Cross Infection
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Infant
/
Newborn
Country/Region as subject:
America do sul
/
Argentina
Language:
Es
Journal:
Rev. argent. microbiol
Journal subject:
MICROBIOLOGIA
Year:
2001
Type:
Article