Protective immunity induced by a Yersinia enterocolitica serovar 0: 8 cellular extract
Biocell
; 20(3): 235-241, Dec. 1996.
Article
in En
| LILACS
| ID: lil-335995
Responsible library:
BR1.1
ABSTRACT
The purpose of this study was to investigate the protective power of a cellular extract (CE) from Y. enterocolitica 08 grown in condition of expression of chromosomal antigens. Mice were immunized by s.c. route and challenged with 0 LD50 (1 x 10(4) CFU/ml). Immunoblotting showed that CE-specific serum reacted with several CE antigens. Prominent bands, of molecular weights 60 and 35.5, were present in cytoplasmic and membrane fraction, respectively. The lipopolysaccharide (LPS) was detected in CE. These findings suggest that chromosomally-encoded antigens present in CE may induce protection against Y. enterocolitica infection. Both humoral and cellular immune response contribute to protection in mice.
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Index:
LILACS
Main subject:
Yersinia enterocolitica
/
Antigens, Bacterial
Limits:
Animals
Language:
En
Journal:
Biocell
Journal subject:
Clulas
Year:
1996
Type:
Article