Densitometría ósea en niños leucémicos al completar el primer mes de quimioterapia / Bone mineral density in leukemic children after completing one month of chemotherapy
Rev. méd. Chile
; 133(1): 71-76, ene. 2005. tab
Article
in Es
| LILACS
| ID: lil-398018
Responsible library:
CL12.1
ABSTRACT
Background:
An important loss of bone mineral density, associated to pain and fractures, has been reported in children with acute lymphoblastic leukemia (ALL).Aim:
To measure bone mineral density among children with acute lymphoblastic leykemia (ALL) that completed the remission induction phase with chemotherapy, that lasts 30 days. Patients andmethods:
children with ALL, admitted to the oncology unit of a general hospital were considered eligible for the study. body composition and bone mineral density were measured by dual energy x ray absorptiometry (DEXA). each child with ALL was paired with a healthly control.Results:
Fourteen children age 1 to 11 years, completed the study, Spine and femoral bone mineral desities were significantly lower than in their matched controls. No differences in total body bone mineral density or content were observed. Children with ALL had a lower fat free mass and a higher fat mass than their matched controls. There was a significant correlation between fat free mass and bone mineral content.Conclusions:
After one month of chemotherapy, children with ALL had a lower bone mineral density in the spine and femur and a lower fat free mass.
Full text:
1
Index:
LILACS
Main subject:
Bone Density
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Type of study:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
Es
Journal:
Rev. méd. Chile
Journal subject:
MEDICINA
Year:
2005
Type:
Article