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Densitometric analysis of the autogenous demineralized dentin matrix on the dental socket wound healing process in humans
Gomes, Mônica Fernandes; Abreu, Paula Pinheiro de; Morosolli, Aline Rose Cantarelli; Araújo, Marcelo Marotta; Goulart, Maria Das Graças Vilela.
  • Gomes, Mônica Fernandes; Special Health Care Needs Association. São José dos Campos. BR
  • Abreu, Paula Pinheiro de; Bioscience Center for Special Health Care Needs. São José dos Campos. BR
  • Morosolli, Aline Rose Cantarelli; Academic Group of Studies and Research with Laser in Dentistry. São José dos Campos. BR
  • Araújo, Marcelo Marotta; São Paulo State University. School of Dentistry of São José dos Campos. Department of Surgery, Periodontology and Radiology. São José dos Campos. BR
  • Goulart, Maria Das Graças Vilela; São Paulo State University. School of Dentistry of São José dos Campos. São José dos Campos. BR
Braz. oral res ; 20(4): 324-330, Oct.-Dec. 2006. ilus, tab, graf
Article in English | LILACS | ID: lil-440180
ABSTRACT
The aim of this study was to evaluate the effects of the autogenous demineralized dentin matrix (ADDM) on the third molar socket wound healing process in humans, using the guided bone regeneration technique and a polytetrafluoroethylene barrier (PTFE). Twenty-seven dental sockets were divided into three groups dental socket (Control), dental socket with PTFE barrier (PTFE), and dental socket with ADDM slices associated to PTFE barrier (ADDM + PTFE). The dental sockets were submitted to radiographic bone densitometry analysis and statistical analysis on the 15th, 30th, 60th and 90th days using analysis of variance (ANOVA) and Tukey's test (p £ 0.05). The radiographic analysis of the ADDM + PTFE group showed greater homogeneity of bone radiopacity than the Control group and the PTFE group, during all the observation times. The dentin matrix gradually disappeared from the dental socket during the course of the repair process, suggesting its resorption during the bone remodeling process. It was concluded that the radiographic bone density of the dental sockets treated with ADDM was similar to that of the surrounding normal bone on the 90th day. The ADDM was biocompatible with the bone tissue of the surgical wounds of human dental sockets. The radiographic analysis revealed that the repair process was discreetly faster in the ADDM + PTFE group than in the Control and PTFE groups, although the difference was not statistically significant. In addition, the radiographic image of the ADDM + PTFE group suggested that its bone architecture was better than that of the Control and PFTE groups.
RESUMO
O objetivo desta pesquisa foi avaliar a reparação óssea em alvéolos dentários após exodontia dos terceiros molares inferiores em humanos, com implantação de matriz dentinária desmineralizada autógena (MDDA) na cavidade e cobertura desta com barreira de politetrafluoretileno (PTFE). Foram selecionados 27 dentes, os quais foram divididos em três grupos alvéolo dentário (Controle), alvéolo dentário com barreira de PTFE (PTFE) e alvéolo dentário com fatias de MDDA associada à barreira de PTFE (MDDA + PTFE). O alvéolo dentário foi submetido à análise de densitometria radiográfica e à análise estatística no 15°, 30°, 60° e 90° dias, utilizando-se a análise de variância (ANOVA) e teste de Tukey (p < 0,05). A análise radiográfica do grupo MDDA + PTFE mostrou maior homogeneidade na radiopacidade do trabeculado ósseo do que no grupo controle e grupo PTFE, durante todos os períodos de observação. A matriz dentinária foi desaparecendo do alvéolo dentário durante a evolução do processo de reparo, sugerindo sua reabsorção durante o processo de remodelação óssea. Concluiu-se que a densidade óssea radiográfica do alvéolo dentário tratado com MDDA foi similar à do osso normal circunjacente no 90° dia. A MDDA foi biocompatível com o tecido ósseo, quando implantada nos alvéolos dentários cruentos de humanos. Na análise radiográfica, pode-se verificar que o processo de reparo foi discretamente mais rápido no grupo MDDA + PTFE do que no grupo Controle e no grupo PTFE, porém não houve diferença estatística significante. Além disso, a imagem radiográfica sugeriu que a arquitetura óssea do grupo MDDA + PTFE foi melhor do que a arquitetura óssea do grupo controle e grupo PTFE.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Polytetrafluoroethylene / Wound Healing / Bone Regeneration / Guided Tissue Regeneration, Periodontal / Tooth Socket / Dentin Limits: Adolescent / Adult / Female / Humans / Male Language: English Journal: Braz. oral res Journal subject: Dentistry Year: 2006 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: Academic Group of Studies and Research with Laser in Dentistry/BR / Bioscience Center for Special Health Care Needs/BR / Special Health Care Needs Association/BR / São Paulo State University/BR

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Full text: Available Index: LILACS (Americas) Main subject: Polytetrafluoroethylene / Wound Healing / Bone Regeneration / Guided Tissue Regeneration, Periodontal / Tooth Socket / Dentin Limits: Adolescent / Adult / Female / Humans / Male Language: English Journal: Braz. oral res Journal subject: Dentistry Year: 2006 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: Academic Group of Studies and Research with Laser in Dentistry/BR / Bioscience Center for Special Health Care Needs/BR / Special Health Care Needs Association/BR / São Paulo State University/BR