Regional differences in veins wall viscosity, compliance. energetics and damping: analysis of the pressure-diameter relationship during cyclical overloads
Biol. Res
; 41(2): 227-233, 2008. tab, graf
Article
in En
| LILACS
| ID: lil-495757
Responsible library:
BR1.1
ABSTRACT
Background:
The characterization of the dynamic process of veins walls is essential to understand venous functioning under normal and pathological conditions. However, little work has been done on dynamic venous properties.Aim:
To characterize vein compliance (C), viscosity (η), peak-strain (W St) and dissipated (W D) energy, damping (ξ), and their regional differences in order to evalúate their role in venous functioning during volume-pressure overloads.Methods:
In a mock circulation, pressure (P) and diameter (D) of different veins (anterior cava, jugular and femoral; from 7 sheep), were registered during cyclical volume-pressure pulses. From the P-D relationship, C, W St and ξ (at low and high P-D leveis), η and W D were calculated. Resulls For each vein there were P-dependent differences in biomechanical, energetics, and damping capability. There were regional-differences in C, η), W St and W D (p<0.05), but not in ξ.Conclusión:
The regional-dependent differences in dynamics and energetics, and regional-similitude in damping could be important to ensure venous functioning during acute overloads. The lower C and higher W St and W D found in back-limb veins (femoral), commonly submitted to high volume-pressure loads (i.e. during walking), could be considered relevant to ensure adequate venous system functionality and venous wall protection simultaneously.Key words
Full text:
1
Index:
LILACS
Main subject:
Vena Cava, Inferior
/
Blood Pressure
/
Blood Volume
/
Femoral Vein
/
Jugular Veins
Limits:
Animals
Language:
En
Journal:
Biol. Res
Journal subject:
BIOLOGIA
Year:
2008
Type:
Article