Low energy laser for prevention of oral mucositis in patients receiving radiotherapy and/or chemotherapy in Pernambuco Cancer Hospital
Appl. cancer res
; 27(4): 182-187, 2007.
Article
in En
| LILACS, Inca
| ID: lil-497102
Responsible library:
BR30.1
ABSTRACT
Oral mucositis induced by antineoplastic therapy causes wide-range pain and discomfort resulting in decreased quality of life. The present study evaluated the benefits of low intensity laser and 0.12% chlorhexidine gluconate in the prevention of oral mucositis induced by radiation, associated or not with chemotherapy, and considered degrees/severity, time of appearanceof the lesions and functional loss. Eighty-four outpatients were considered and 49 were included in this study and dividedinto two groups Group 1 received laser treatments in three stages, starting three days before treatment until the end of therapy. Group 2 was instructed to do daily mouth rinses with chlorhexidine gluconate. The prevalence of clinical mucositis was 49%, and of functional mucositis, 28.6%, when the two groups were considered together. This percentage was smaller in the laser group, 44% for the clinical mucositis group and 24% for the functional. The two protocols were well tolerated andshowed benefits, mainly from the point of view of functionality, and delayed the onset and development of mucositis.
Full text:
1
Index:
LILACS
Main subject:
Radiotherapy
/
Chlorhexidine
/
Preventive Dentistry
/
Drug Therapy
/
Mucositis
/
Laser Therapy
/
Neoplasms
Type of study:
Guideline
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Appl. cancer res
Journal subject:
NEOPLASIAS
Year:
2007
Type:
Article