Penfigóide cicatricial no trato aerodigestivo superior: relato de dois casos / Cicatricial pemphygoid in the upper aerodigestive tract: report of two cases
Rev. bras. otorrinolaringol
;
74(6): 941-944, nov.-dez. 2008. ilus
Article
in English, Portuguese
| LILACS
| ID: lil-503641
RESUMO
Penfigóide Cicatricial (Penfigóide Cicatricial de Membrana Mucosa) é uma doença auto-imune inflamatória crônica caracterizada pela presença de bolhas subepiteliais em membranas mucosas e, ocasionalmente na pele. Pode haver acometimento oral, nasal, faríngeo, laríngeo, ocular, esofágico, anogenital e de pele, predominantemente em pacientes na quinta e sexta décadas de vida. O tratamento preconizado inclui corticóides sistêmicos e agentes imunossupressores. Descrevemos neste trabalho dois casos com a doença em atividade, sendo que um evoluiu com complicação séptica pelo uso de imunossupressor e outro que apresentou estenose supraglótica exigindo traqueotomia.
ABSTRACT
Cicatricial pemphygoid (mucous membrane cicatricial pemphygoid) is a chronic autoimmune inflammatory disease characterized by subepithelial bubbles in mucous membranes and, occasionally on the skin. It may affect the mouth, the nose, pharynx, larynx, the eyes, esophagus, anus, genitals and skin; especially affecting patients between fifty and sixty years of life. Treatment includes systemic steroids and immunosuppressive agents. In the present paper we describe two cases with the active disease, and one of them had sepsis because of using immunosuppressive agents and another that presented supraglottic stenosis requiring tracheostomy.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Pemphigoid, Benign Mucous Membrane
/
Mouth Diseases
Type of study:
Diagnostic study
Limits:
Aged
/
Humans
/
Male
Language:
English
/
Portuguese
Journal:
Rev. bras. otorrinolaringol
Journal subject:
Otolaryngology
Year:
2008
Type:
Article
Affiliation country:
Brazil
Similar
MEDLINE
...
LILACS
LIS