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Chemical investigation of Spigelia anthelmia Linn. used in Brazilian folk medicine as anthelmintic
Morais, Selene Maia de; Beviláqua, Cláudia Maria Leal; Souza, Júlia Aprecida L. de; Assis, Luciana Moura de.
Affiliation
  • Morais, Selene Maia de; Universidade Estadual do Ceará. Centro de Ciências e Tecnologia. Departamento de Física e Química. Fortaleza. BR
  • Beviláqua, Cláudia Maria Leal; Universidade Estadual do Ceará. Faculdade de Veterinária. Fortaleza. BR
  • Souza, Júlia Aprecida L. de; Universidade Estadual do Ceará. Centro de Ciências e Tecnologia. Departamento de Física e Química. Fortaleza. BR
  • Assis, Luciana Moura de; Universidade Estadual do Ceará. Faculdade de Veterinária. Fortaleza. BR
Rev. bras. farmacogn ; 12(supl.1): 81-82, 2002. ilus
Article in En | LILACS | ID: lil-528763
Responsible library: BR1.1
ABSTRACT
An ethanol extract of aerial parts of Spigelia anthelmia was submitted to vacuum column chromatography being eluted with hexane, chloroform, ethyl acetate and methanol. The four extracts were assayed for anthelmintic activity against Haemonchus contortus, the main nematode in caprines. The ethyl acetate extract showed the strongest anthelmintic activity and the chemical study of this extract revealed as main constituents the alkaloid spiganthine and 3,7-dihydroxy-3',4'- dimethoxyflavone.
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Full text: 1 Index: LILACS Country/Region as subject: America do sul / Brasil Language: En Journal: Rev. bras. farmacogn Journal subject: FARMACIA Year: 2002 Type: Article
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Full text: 1 Index: LILACS Country/Region as subject: America do sul / Brasil Language: En Journal: Rev. bras. farmacogn Journal subject: FARMACIA Year: 2002 Type: Article