Hepatite granulomatosa em bovino causada por Mycobacterium avium subsp. paratuberculosis / Granulomatous hepatitis in cattle caused by Mycobacterium avium subsp. paratuberculosis
Arq. bras. med. vet. zootec
; 62(6): 1495-1498, dez. 2010. ilus
Article
in Pt
| LILACS
| ID: lil-576052
Responsible library:
BR68.1
ABSTRACT
Samples from intestines, liver, and lymph nodes were collected from a dairy steer with clinical suspicion of paratuberculosis. The samples were processed for histologic examination with hematoxylin-eosin and Zihel-Neelsen (ZN) staining for the detection of acid-fast bacilli (AFB), and submitted to immunohistochemistry (IHC). Macroscopic changes were observed in the small intestines, with thickening and corrugation of the mucosa. The main microscopic changes were found in small intestines, lymph vessels in the mesentery, and mesenteric lymph nodes characterized by enteritis, lymphangiectasia, and lymphadenitis. Liver presented with granulomatous hepatitis, an uncommon histopathological feature for paratuberculosis. The clinical features associated with positive culture of Mycobacterium avium subsp. paratuberculosis and detection of AFB by ZN and IHC in the cytoplasm of macrophages (epithelioid) in the intestinal mucosa and submucosa, lymph nodes, and liver were important to confirm the diagnosis of paratuberculosis.
Key words
Full text:
1
Index:
LILACS
Main subject:
Hepatitis
/
Mycobacterium
Limits:
Animals
Language:
Pt
Journal:
Arq. bras. med. vet. zootec
Journal subject:
MEDICINA VETERINARIA
Year:
2010
Type:
Article