Alkaloids and triterpene from Almeidea coerulea (Nees and Mart.) a. St.-Hil. and anti-leishmanial activity
Braz. arch. biol. technol
;
54(1): 61-66, Jan.-Feb. 2011. ilus, graf, tab
Article
in English
| LILACS
| ID: lil-576759
ABSTRACT
The dichloromethane extract of Almeidea coerulea stems yielded the (11-hydroxyrutaecarpine alkaloid reported for the first time from this species) and the triterpene (28-hydroxy-28, 29-dihydrolupeol). The dictamine, skimianine, sitosterol and stigmasterol were also isolated from methanol extract. Extracellular forms of Leishmania amazonensis (promastigotes) was tested with dichloromethane extract and 28-hydroxy-28, 29-dihydrolupeol with showed anti-leishmanial activity above 0.1 mg/mL and 75µg/mL (inhibited 50 percent promastigote growth), respectively.
Full text:
Available
Index:
LILACS (Americas)
Language:
English
Journal:
Braz. arch. biol. technol
Journal subject:
Biology
Year:
2011
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Centro de Ensino Superior/BR
/
Universidade Estadual de Maringá/BR
/
Universidade Federal de São Carlos/BR
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