Pleomorphic adenoma with extensive squamous metaplasia and keratin cyst formations in minor salivary gland: a case report
J. appl. oral sci
;
19(2): 182-188, May-Apr. 2011. ilus
Article
in English
| LILACS
| ID: lil-586039
ABSTRACT
Pleomorphic adenoma (PA), the most common salivary gland tumor, accounts for 54 to 65 percent of all salivary gland neoplasias and 80 percent of the benign salivary gland tumors. It most frequently affects the parotid gland, followed by the submandibular and the minor salivary glands. Microscopically, mucous, sebaceous, oncocytic and squamous metaplasia, sometimes with the formation of keratin pearls, may be present, but the latter rarely results in the formation of extensive keratin-flled cysts lined by squamous epithelium. Extensive squamous metaplasia can be mistaken for malignancy, including mucoepidermoid carcinoma and squamous cell carcinoma. Here, we present an unusual case of PA with extensive squamous metaplasia and keratin cyst formations in a minor salivary gland, and discuss its microscopic features, including the immunohistochemical characteristics, and differential diagnosis of this uncommon presentation.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Salivary Glands, Minor
/
Salivary Gland Neoplasms
/
Adenoma, Pleomorphic
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
J. appl. oral sci
Journal subject:
Dentistry
Year:
2011
Type:
Article
Affiliation country:
Brazil
/
Guatemala
Institution/Affiliation country:
Centro Clinico de Cabeza y Cuello/GT
/
José do Rosário Vellano University/BR
/
University of São Paulo/BR
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