Fuente de infección de Bordetella pertussis en lactantes hospitalizados por coqueluche / Source of infection in young infants hospitalized with Bordetella pertussis
Rev. méd. Chile
; 139(4): 448-454, abr. 2011. ilus
Article
in Es
| LILACS
| ID: lil-597639
Responsible library:
BR1.1
ABSTRACT
Background:
Despite pertussis vaccination, very young infants have the highest rates of morbidity and mortality caused by the microorganism.Aim:
To determine the source of Pertussis infection in infants aged six months or less in Chile. Material andMethods:
Twenty six household contacts of 10 young infants hospitalized with confirmed Pertussis were studied for the presence of Bordetella Pertussis by polyme-rase chain reaction (PCR). Clinical and demographic data were analyzed.Results:
Respiratory symptoms were present in 20 (77 percent) contacts, being cough the most common. Pertussis cases were identifed in every household and in 18 (72 percent) of the household members. four members with B.pertussis were asymptomatic. Source of infection was identifed in 80 percent (8/10) of the infant cases with ages ranging from 6 to 62 years. Half of primary cases had positive PCR and their cough duration was significantly shorter compared to primary cases with negative PCR.Conclusions:
B. pertussis transmission to young infants occurred mainly within the household where adults are generally the source of the infection. Risk factors for infant infection are the same as in developed countries. Therefore, the same strategies, such as routine vaccination in adolescents and adults or cocoon strategy, will help to prevent this disease in infants.Key words
Full text:
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Index:
LILACS
Main subject:
Bordetella pertussis
/
Whooping Cough
/
Family Characteristics
/
Contact Tracing
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Country/Region as subject:
America do sul
/
Chile
Language:
Es
Journal:
Rev. méd. Chile
Journal subject:
MEDICINA
Year:
2011
Type:
Article