Prenatally programmed hypertension: role of maternal diabetes
Braz. j. med. biol. res
; 44(9): 899-904, Sept. 2011. ilus
Article
in En
| LILACS
| ID: lil-599660
Responsible library:
BR1.1
ABSTRACT
Epidemiological and experimental studies have led to the hypothesis of the fetal origin of adult diseases, suggesting that some adult diseases might be determined before birth by altered fetal development. Maternal diabetes subjects the fetus to an adverse environment that has been demonstrated to result in metabolic, cardiovascular and renal impairment in the offspring. The growing amount of obesity in young females in developed and some developing countries should contribute to increasing the incidence of diabetes among pregnant women. In this review, we discuss how renal and extrarenal mechanisms participate in the genesis of hypertension induced by a diabetic status during fetal development.
Key words
Full text:
1
Index:
LILACS
Main subject:
Pregnancy in Diabetics
/
Diabetes Mellitus
/
Hypertension
Type of study:
Etiology_studies
/
Risk_factors_studies
Limits:
Animals
/
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
Braz. j. med. biol. res
Journal subject:
BIOLOGIA
/
MEDICINA
Year:
2011
Type:
Article
/
Congress and conference