Xylitol inhibits J774A.1 macrophage adhesion in vitro
Braz. arch. biol. technol
; 54(6): 1211-1216, Nov.-Dec. 2011.
Article
in En
| LILACS
| ID: lil-608443
Responsible library:
BR1.1
ABSTRACT
The aim of this work was to evaluate the effect of xylitol on J774A.1 macrophage adhesion. Adhesion consisted of a three-hour interval, at room temperature, followed by washing and cell incubation at 37ºC/5 percent CO2/ 48h. Xylitol was used to treat the cells either before (for 24h) or after the cell incubation (for 48h) at 5 percent as final concentration in both the situations. It was found that xylitol was effective in preventing the adhesion in both the conditions in spite of the former being 100-fold greater and significant (p < 0.001). The results pointed to an important xylitol action on macrophage adhesion, which should be further investigated as an inflammatory control.
Full text:
1
Index:
LILACS
Language:
En
Journal:
Braz. arch. biol. technol
Journal subject:
BIOLOGIA
Year:
2011
Type:
Article
/
Project document