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A rational approach to the diagnosis of polycystic ovarian syndrome during adolescence / Uma abordagem racional do diagnóstico da síndrome dos ovários policísticos na adolescência
Merino, Paulina M; Codner, Ethel; Cassorla, Fernando.
  • Merino, Paulina M; University of Chile. School of Medicine. Institute of Maternal and Child Research. CL
  • Codner, Ethel; University of Chile. School of Medicine. Institute of Maternal and Child Research. CL
  • Cassorla, Fernando; University of Chile. School of Medicine. Institute of Maternal and Child Research. CL
Arq. bras. endocrinol. metab ; 55(8): 590-598, nov. 2011. ilus
Article in English | LILACS | ID: lil-610460
ABSTRACT
Polycystic ovarian syndrome (PCOS) is a lifelong disorder characterized by hyperandrogenism and ovulatory dysfunction, with a wide spectrum of clinical symptoms and signs. Three different sets of diagnostic criteria have been established in order to define this disease in adult women, but there is controversy regarding the use of these criteria in adolescence. During puberty, the adult criteria for ovulatory dysfunction does not seem applicable, because an irregular menstrual pattern and a decreased ovulatory rate is a physiologic event during this period of life. Also, a higher prevalence of polycystic ovarian morphology (PCOM) may be observed during this period, so PCOM is not a useful criterion to define PCOS in young women. These findings suggest that a key factor to diagnose to PCOS during adolescence is hyperandrogenism. In addition, since PCOM is not clearly associated with hyperandrogenism during this period of life, the term "polycystic ovarian syndrome" during adolescence creates confusion and may be misleading.
RESUMO
A síndrome dos ovários policísticos (SOP) é uma desordem que afeta pacientes por toda a vida e é caracterizada por hiperandrogenismo e disfunção ovariana, com um amplo leque de sintomas e sinais clínicos. Três diferentes conjuntos de critérios diagnósticos foram estabelecidos para definir essa doença em mulheres adultas, mas existem controvérsias relacionadas ao uso desses critérios na adolescência. Durante a puberdade, o critério de disfunção ovariana usado em adultos não parece aplicável, porque um padrão menstrual irregular e uma menor taxa de ovulação são eventos fisiológicos nesse período da vida. Além disso, uma maior prevalência de morfologia ovariana policística (MOP) pode ser observada nesse período, de forma que a MOP não é um critério útil para se definir a SOP em mulheres jovens. Esses achados sugerem que o hiperandrogenismo é um fator-chave para o diagnóstico da SOP na adolescência. Além disso, como a MOP não está claramente associada com o hiperandrogenismo durante esse período da vida, o termo "síndrome dos ovários policísticos" durante a adolescência cria confusão e pode ser errôneo.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Polycystic Ovary Syndrome / Hyperandrogenism / Diagnostic Techniques, Obstetrical and Gynecological Type of study: Diagnostic study / Etiology study / Risk factors Limits: Adolescent / Female / Humans Language: English Journal: Arq. bras. endocrinol. metab Journal subject: Endocrinology / Metabolism Year: 2011 Type: Article Affiliation country: Chile Institution/Affiliation country: University of Chile/CL

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Full text: Available Index: LILACS (Americas) Main subject: Polycystic Ovary Syndrome / Hyperandrogenism / Diagnostic Techniques, Obstetrical and Gynecological Type of study: Diagnostic study / Etiology study / Risk factors Limits: Adolescent / Female / Humans Language: English Journal: Arq. bras. endocrinol. metab Journal subject: Endocrinology / Metabolism Year: 2011 Type: Article Affiliation country: Chile Institution/Affiliation country: University of Chile/CL