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Assessment of antidiarrhoeal activity of Desmostachya bipinnata L. (Poaceae) root extracts / Evaluación de la actividad de antidiarreica de extractos de la raíz de Desmostachya bipinnata L. (Poaceae)
Hegde, Medha M; Lakshman, K; Girija, K; Kumar, BS Ashok; Lakshmiprasanna, V.
  • Hegde, Medha M; PES College of Pharmacy. Department of Pharmacognosy. Bangalore. IN
  • Lakshman, K; PES College of Pharmacy. Department of Pharmacognosy. Bangalore. IN
  • Girija, K; PES College of Pharmacy. Department of Pharmacognosy. Bangalore. IN
  • Kumar, BS Ashok; Sri KV College of Pharmacy. Department of Pharmacognosy. Chikkaballapur. IN
  • Lakshmiprasanna, V; PES College of Pharmacy. Department of Pharmacognosy. Bangalore. IN
Article in English | LILACS | ID: lil-613286
ABSTRACT
Desmostachya bipinnata root has been used in the Indian traditional system of medicine for treatment of diarrhoea and dysentery. The antidiarrhoeal effect of both alcoholic and aqueous extracts of the roots of Desmostachya bipinnata were studied in rats against castor oil induced diarrhoea and charcoal meal test at the doses of 200 and 400 mg/kg body weight. The alcoholic extract and to a lesser extent aqueous extract significantly reduced the weight of the faces and decreased the propulsion of charcoal meal through the gastrointestinal tract. The phytochemical screening of the extracts showed the presence of alkaloids, glycosides, flavonoids, tannins, phytosterol, terpenoids, polyphenolics, protein and carbohydrates. These results may support the fact that this plant is used traditionally to cure diarrhoea.
RESUMEN
La raíz de Desmostachya bipinnata ha sido utilizada en el sistema tradicional de medicina Hindú para el tratamiento de diarrea y disentería. El efecto antidiarreico de los extractos alcohólicos y acuosos de los extractos de la raíz de Desmostachya bipinnata fueron estudiados en ratas, utilizando la diarrea inducida por aceite de castor y el ensayo de la prueba por carbón en dosis de 200 y 400 mg/kg de peso corporal. El extracto alcohólico y en menor grado, el extracto acuoso, redujeron significativamente la propulsión de carbón a través del tracto gastrointestinal. El análisis de los extractos mostrarón la presencia de alcaloides, glicósidos, flavonoides, taninos, fitoesterol, terpenoides, polifenoles, proteínas y carbohidratos. Estos resultados pueden apoyar el hecho de que esta planta sea usada tradicionalmente para curar la diarrea.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Plant Extracts / Plant Roots / Diarrhea / Ethanol / Poaceae / Antidiarrheals Limits: Animals Language: English Journal: Bol. latinoam. Caribe plantas med. aromát Journal subject: Botany / Medicine / Plantas Medicinais / Terapias Complementares Year: 2010 Type: Article Affiliation country: India Institution/Affiliation country: PES College of Pharmacy/IN / Sri KV College of Pharmacy/IN

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Full text: Available Index: LILACS (Americas) Main subject: Plant Extracts / Plant Roots / Diarrhea / Ethanol / Poaceae / Antidiarrheals Limits: Animals Language: English Journal: Bol. latinoam. Caribe plantas med. aromát Journal subject: Botany / Medicine / Plantas Medicinais / Terapias Complementares Year: 2010 Type: Article Affiliation country: India Institution/Affiliation country: PES College of Pharmacy/IN / Sri KV College of Pharmacy/IN