Anticaries effect of dentifrices with calcium citrate and sodium trimetaphosphate
J. appl. oral sci
; 20(1): 94-98, Jan.-Feb. 2012. graf
Article
in En
| LILACS
| ID: lil-618160
Responsible library:
BR1.1
ABSTRACT
Because of the growing concerns regarding fluoride ingestion by young children and dental fluorosis, it is necessary to develop new dentifrices. OBJECTIVE:
The aim of this study was to evaluate the effect of dentifrices with calcium citrate (Cacit) and sodium trimetaphosphate (TMP) on enamel demineralization. MATERIAL ANDMETHODS:
Enamel blocks (n=70), previously selected through surface hardness analysis, were submitted to daily treatment with dentifrices diluted in artificial saliva and to a pH-cycling model. The fluoride concentration in dentifrices was 0, 250, 450, 550, 1,000 and 1,100 µg F/g. CrestTM was used as a positive control (1,100 mg F/g). Cacit (0.25 percent) and TMP (0.25 percent) were added to dentifrices with 450 and 1,000 µg F/g. Surface hardness was measured again and integrated loss of subsurface hardness and fluoride concentration in enamel were calculated. Parametric and correlation tests were used to determine difference (p<0.05) and dose-response relationship between treatments.RESULTS:
The addition of Cacit and TMP did not provide a higher fluoride concentration in enamel, however it reduced (p<0.05) mineral loss when compared to other dentifrices; the dentifrice with Cacit and TMP and a low fluoride concentration presented similar results when compared to a dentifrice with 1,100 mg F/g (p>0.05).CONCLUSIONS:
Dentifrices with 450 and 1,000 µg F/g, Cacit and TMP were as effective as a gold standard one.Key words
Full text:
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Index:
LILACS
Main subject:
Polyphosphates
/
Cariostatic Agents
/
Tooth Demineralization
/
Calcium Citrate
/
Dentifrices
/
Fluorides
Type of study:
Clinical_trials
/
Evaluation_studies
Limits:
Humans
Language:
En
Journal:
J. appl. oral sci
Journal subject:
ODONTOLOGIA
Year:
2012
Type:
Article