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Executive attention and working memory in narcoleptic outpatients / Atenção executiva e memória de trabalho em pacientes com narcolepsia
Moraes, Mirleny; Rossini, Sueli; Reimão, Rubens.
  • Moraes, Mirleny; University of São Paulo Medical School. Hospital das Clínicas. Division of Clinical Neurology. Sleep Medicine Advanced Research Group. São Paulo. BR
  • Rossini, Sueli; FMUSP. Hospital das Clínicas. Division of Clinical Neurology. Sleep Medicine Advanced Research Group. São Paulo. BR
  • Reimão, Rubens; FMUSP. Hospital das Clínicas. Division of Clinical Neurology. Sleep Medicine Advanced Research Group. São Paulo. BR
Arq. neuropsiquiatr ; 70(5): 335-340, May 2012. tab
Article in English | LILACS | ID: lil-622582
ABSTRACT

OBJECTIVE:

This pioneering study aimed to evaluate executive attention and working memory in Brazilian narcoleptic outpatients.

METHODS:

Narcoleptic group 19 treated narcoleptic outpatients (13 F; 6 M) (mean age=37.58; SD = 8.93); control group 19 subjects (15 F; 4 M) (mean age=34.42; SD=12.31). INSTRUMENTS Epworth Sleepiness Scale - Brazilian Portuguese Version (ESS-BR), Victoria Stroop Test (VST), Trail Making Test (TMT) and Letter-Number Sequencing (LNS) of WAIS-III.

RESULTS:

Significant difference at Excessive Daytime Sleepiness (EDS) (p<0.001) and at working memory (p=0.009) with worse results for narcoleptic patients. Patients were slower at VST-1 (p=0.002), VST-2 (p=0.045) and at TMT-A (p=0.016), TMT-B (p=0.006) and B-A (p=0.024).

CONCLUSION:

Narcoleptic patients showed higher degrees of EDS, an impaired executive attention at a temporal level and lower performance in working memory when compared to normal controls.
RESUMO

OBJETIVO:

Este estudo pioneiro teve como objetivo avaliar a atenção executiva e a memória de trabalho em pacientes brasileiros com narcolepsia.

MÉTODOS:

Grupo-estudo 19 narcolépticos tratados (13 M; 6 H), com média de idade de 37,58 anos, DP=8,93; grupo-controle 19 sujeitos (15 M; 4 H), com média de idade de 34,42 anos, DP=12,31. UTILIZARAM-SE a Escala de Sonolência de Epworth-BR, Victoria Stroop Test (VST), Trail Making Test (TMT) e Sequência de Números e Letras (SNL) da WAIS-III.

RESULTADOS:

Houve diferença significativa nos graus de Sonolência Diurna Excessiva (SDE) (p<0,001) e na memória de trabalho (p=0,009), com piores resultados para o grupo-estudo. Do mesmo modo, verificaram-se tempos aumentados no grupo-estudo para execução do VST-1 (p=0,002), VST-2 (p=0,045) e TMT-A (p=0,016), e TMT-B (p=0,006) e B-A (p=0,024).

CONCLUSÃO:

Os pacientes com narcolepsia apresentaram graus mais elevados de SDE, prejuízo na atenção executiva em nível temporal e desempenho inferior da memória de trabalho em relação aos sujeitos-controles.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Psychomotor Performance / Attention / Executive Function / Memory, Short-Term / Narcolepsy Type of study: Observational study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2012 Type: Article Affiliation country: Brazil Institution/Affiliation country: FMUSP/BR / University of São Paulo Medical School/BR

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Full text: Available Index: LILACS (Americas) Main subject: Psychomotor Performance / Attention / Executive Function / Memory, Short-Term / Narcolepsy Type of study: Observational study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2012 Type: Article Affiliation country: Brazil Institution/Affiliation country: FMUSP/BR / University of São Paulo Medical School/BR