Falla cardíaca aguda asociada a bloqueo aurículo ventricular congénito completo secundario a lupus neonatal: reporte de una serie de casos / Acute heart failure associated with congenital complete atrioventricular block due to neonatal lupus: case serie report
Rev. colomb. reumatol
; 17(3): 178-181, jul.-sep. 2010. ilus, tab
Article
in Es
| LILACS
| ID: lil-636833
Responsible library:
CO356.9
RESUMEN
El lupus neonatal (LN) comprende un conjunto de síndromes clínicos caracterizados por anticuerpos maternos contra el complejo RNA proteína (Ro/SSA o La/SSB) que atraviesan la placenta y potencialmente llevan a daño tisular fetal. Poco se conoce acerca de otras manifestaciones cardíacas del LN diferentes al bloqueo cardíaco congénito (BCC), como la falla cardíaca (ICC). Se reportan cuatro casos de LN con BCC e ICC aguda en los primeros tres días de vida en promedio. No se presentaron complicaciones o muertes a los 4,9 meses de seguimiento. Todos los neonatos tenían títulos altos de anti-Ro al momento del diagnóstico.
ABSTRACT
Neonatal lupus (NL) defines a set of clinical syndromes characterized by maternal autoantibodies against the RNA protein complex (Ro/SSA or La/SSB) that cross the placenta and potentially lead to fetal tissue damage. Little is known about other cardiac manifestations of NL different from congenital heart block (CHB), as heart failure (HF). Four cases of LN with BCC and acute HF at the first three days of life on average were reported. No complications or deaths were reported at 4,9 months of follow-up. All infants had anti-Ro high titles at the time of diagnosis.
Key words
Full text:
1
Index:
LILACS
Main subject:
Placenta
/
Infant, Newborn
/
Atrioventricular Block
Type of study:
Diagnostic_studies
/
Risk_factors_studies
Limits:
Humans
/
Infant
/
Newborn
Language:
Es
Journal:
Rev. colomb. reumatol
Journal subject:
REUMATOLOGIA
Year:
2010
Type:
Article