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Tuberculous meningitis: a report of 60 adult cases / Meningitis tuberculosa: reporte de 60 casos adultos
Ersöz, M; Yildirmak, MT; Gedik, H; Şimşek, F; Kantürk, A; Iris, NE; Dinç, E.
Affiliation
  • Ersöz, M; Minsitry of Health Okmeydani Training and Research Hospital. Minsitry of Health Okmeydani Training and Research Hospital. TR
  • Yildirmak, MT; Minsitry of Health Okmeydani Training and Research Hospital. Minsitry of Health Okmeydani Training and Research Hospital. TR
  • Gedik, H; Minsitry of Health Okmeydani Training and Research Hospital. Minsitry of Health Okmeydani Training and Research Hospital. TR
  • Şimşek, F; Minsitry of Health Okmeydani Training and Research Hospital. Minsitry of Health Okmeydani Training and Research Hospital. TR
  • Kantürk, A; Minsitry of Health Okmeydani Training and Research Hospital. Minsitry of Health Okmeydani Training and Research Hospital. TR
  • Iris, NE; Minsitry of Health Okmeydani Training and Research Hospital. Minsitry of Health Okmeydani Training and Research Hospital. TR
  • Dinç, E; Minsitry of Health Okmeydani Training and Research Hospital. Minsitry of Health Okmeydani Training and Research Hospital. TR
West Indian med. j ; West Indian med. j;61(6): 592-597, Sept. 2012. tab
Article in En | LILACS | ID: lil-672963
Responsible library: BR1.1
ABSTRACT

OBJECTIVE:

This was to evaluate the history, clinical and laboratory findings, outcome and prognosis of patients with tuberculous meningitis (TBM).

METHOD:

Between 1998 and 2009, 60 patients with TBM were evaluated, retrospectively.

RESULT:

Overall, 60 patients were selected, of which 33 (55%) were male. The patients' ages ranged from 14 to 62 years. In the majority of the patients, disease was in an advanced stage on admission (66% in stage III according to the British Research Council neurological criteria). The rate of complications was highest among patients in stages II and III with an overall mortality rate of 6.6% (n= 2 of stage II patients and n= 2 of stage III patients).

CONCLUSIONS:

Earlier admission of the patients with TBM could provide better outcomes with regard to sequelae and mortality. Fatal cases presented with rapid deterioration and were refractory to treatment.
RESUMEN

OBJETIVO:

El propósito de este trabajo fue evaluar la historia, los hallazgos clínicos y de laboratorio, la evolución, y la prognosis de pacientes con meningitis tuberculosa (MTB).

MÉTODO:

Entre 1998 y 2009, se evaluaron 60 pacientes con TBM, retrospectivamente.

RESULTADOS:

En general, se seleccionaron 60pacientes, de los cuales 33 (55%) fueron varones. La edad de los pacientes osciló de 14 a 62 años. En la mayoría de los pacientes, la enfermedad se encontraba en etapa avanzada al momento del ingreso (66% en la etapa III de acuerdo con los criterios neurológicos del Consejo Británico de Investigación). La tasa de complicaciones fue más alta entre los pacientes en las etapas IIy III con una tasa de mortalidad general de 6.6% (n = 2 en los pacientes de etapa IIy n = 2 en los pacientes de etapa III).

CONCLUSIONES:

El ingreso temprano de los pacientes con MTB podría proporcionar mejores resultados con respecto a las secuelas y la mortalidad. Los casos fatales se presentaron con deterioro rápido y fueron refractarios al tratamiento.
Subject(s)
Key words
Full text: 1 Index: LILACS Main subject: Tuberculosis, Meningeal / Mycobacterium tuberculosis Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: West Indian med. j Journal subject: MEDICINA Year: 2012 Type: Article
Full text: 1 Index: LILACS Main subject: Tuberculosis, Meningeal / Mycobacterium tuberculosis Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: West Indian med. j Journal subject: MEDICINA Year: 2012 Type: Article