Grosor íntima media carotídeo y asociación con factores de riesgo cardiovascular tradicionales y metabólicos / Association of carotid intima-media thickness with traditional cardiovascular risk and metabolic factors
Rev. méd. Chile
;
141(6): 695-703, jun. 2013. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-687200
ABSTRACT
Background:
Carotid intima-media thickness (IMT) is a surrogate marker of subclinical atherosderosis and is associated with cardiovascular risk factors (CVRF)Aim:
To analyze the association of CVRF and metabolic factors (MF) with IMT, and if the clustering of these factors modify IMT. Material andMethods:
Cross sectional study in 187 participants aged 46±10years (53% male) without CV disease. Weight, height, waist circumference (WC), blood pressure, fasting plasma glucose and lipid profile were measured. Abdominal obesity (AOb) was defined by ATP III criteria. Mean carotid IMT was measured at the far watt of the common carotid artery. The cutoff point for an abnormally high IMT was set at the 75th IMT percentile of the sample.Results:
The 75th IMT percentile of the sample was 0.67 mm. In a multivariate analysis four factors were significantly related with a high IMT age (odds ratio (OR) 5.3, confidence intervals (CI) 2.2-12.9), dyslipidemia (OR 6.4 CI 2.3-17.9), systolic blood pressure (OR 2.9, CI 1.2-7.1) and AOb (OR 2.9 (IC 1.1-7.2). The presence of Oto 4 of these factors was associated with an IMT increment from 0.54 to 0.71 mm (p < 0,001).Conclusions:
In this sample dyslipidemia, systolic blood pressure and abdominal obesity were the main predictors of a high IMT.
Full text:
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Index:
LILACS (Americas)
Main subject:
Cardiovascular Diseases
/
Carotid Intima-Media Thickness
Type of study:
Diagnostic study
/
Etiology study
/
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2013
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital de Carabineros/CL
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