Studying neurodegenerative diseases in culture models
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
; 35(supl.2): S92-S100, 2013.
Article
in En
| LILACS
| ID: lil-691402
Responsible library:
BR1.1
ABSTRACT
Neurodegenerative diseases are pathological conditions that have an insidious onset and chronic progression. Different models have been established to study these diseases in order to understand their underlying mechanisms and to investigate new therapeutic strategies. Although various in vivo models are currently in use, in vitro models might provide important insights about the pathogenesis of these disorders and represent an interesting approach for the screening of potential pharmacological agents. In the present review, we discuss various in vitro and ex vivo models of neurodegenerative disorders in mammalian cells and tissues.
Key words
Full text:
1
Index:
LILACS
Main subject:
Parkinson Disease
/
Huntington Disease
/
Culture Techniques
/
Alzheimer Disease
/
Amyotrophic Lateral Sclerosis
Type of study:
Etiology_studies
Limits:
Animals
Language:
En
Journal:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Journal subject:
PSIQUIATRIA
Year:
2013
Type:
Article
/
Project document