Use of etoricoxib and dexamethasone for postoperative pain prevention and control in mucogingival surgery: a randomized parallel double-blind clinical trial
Braz. j. oral sci
; 12(4): 345-351, Oct.-Dec. 2013. ilus, tab
Article
in En
| LILACS
| ID: lil-701325
Responsible library:
BR218.1
ABSTRACT
AIM:
To compare the use of etoricoxib and dexamethasone for postoperative pain prevention and control after mucogingival surgery.METHODS:
Fifty-eight patients with indication for mucogingival surgery took part in this randomized parallel double-blind clinical trial. They were divided into three groups (G) G1 - placebo 1 h before surgery; G2 - 8 mg dexamethasone 1 h before surgery; G3 - 90 mg etoricoxib 1 h before surgery. Pain intensity was assessed in donor and recipient sites separately using the 101-point numerical rating scale NRS - 101, every hour for the first 8 h after surgery and three times a day on the following 3 days.RESULTS:
there was a statistically significant difference in the postoperative pain intensity in the donor site between G1 and G3 after 1 h, 2 h, 3 h, 7 h, 8 h and on the second day - in the evening after 32 h; between G1 and G2 after 2 h and 3 h, and between G2 and G3 only after the first hour. Pain intensity in the recipient site was statistically significant between G1 and G3 after 1 and 2 h (p<0.05). In addition, there was a lower ingestion of rescue medication in G2 and in G3 than in G1 (p=0.002).CONCLUSIONS:
the use of a pre-emptive single dose of etoricoxib or dexamethasone may be considered an effective protocol for postoperative pain prevention and control after mucogingival surgery.Key words
Full text:
1
Index:
LILACS
Main subject:
Surgery, Oral
/
Dexamethasone
/
Analgesia
/
Anti-Inflammatory Agents
Type of study:
Clinical_trials
/
Guideline
Limits:
Female
/
Humans
/
Male
Language:
En
Journal:
Braz. j. oral sci
Journal subject:
ODONTOLOGIA
Year:
2013
Type:
Article