Caracterización de la asociación aterosclerosis-osteoporosis en hombres y mujeres: estudio en fallecidos / Characterization of the association between atherosclerosis and osteoporosis in men and women: study of deceased subjects
Rev. cuba. invest. bioméd
; 32(3): 321-337, jul.-sep. 2013.
Article
in Es
| LILACS
| ID: lil-705685
Responsible library:
CU1.1
RESUMEN
Objetivos:
caracterizar la asociación entre las lesiones ateroscleróticas de las arterias coronarias con la osteoporosis de la columna lumbar y de fémur proximal en hombres y mujeres.Métodos:
se estudiaron 79 necropsias, realizando densitometría postmorten de columna lumbar y fémur proximal, clasificando los niveles de densidad mineral ósea (DMO) según T score en normal, osteopenia y osteoporosis; seguido del examen patomorfológico y morfométrico de las tres coronarias epicárdicas principales aplicando el sistema aterométrico, clasificando las lesiones ateroscleróticas como estría adiposa, placa fibrosa y placa grave.Resultados:
la asociación aterosclerosis-osteoporosis mostró características especiales para cada sexo, con predominio significativo de osteoporosis en hombres y de osteopenia en mujeres. Tras remover el efecto del tabaquismo, las diferencias entre los géneros se modificaron, observándose que los fumadores, de ambos sexos, presentaron una DMO y una asociación aterosclerosis-osteoporosis similares.Conclusiones:
la interferencia ejercida por sexo sobre la asociación aterosclerosis-osteoporosis resultó despreciableABSTRACT
Objectives:
characterize the association between atherosclerotic lesions of the coronary arteries and osteoporosis of the lumbar spine and the proximal femur in men and women.Methods:
a study was conducted of 79 necropsies by postmortem densitometry of the lumbar spine and proximal femur. Bone mineral density (BMD) levels were classified according to T score into normal, osteopenia and osteoporosis; followed by pathomorphological and morphometric examination of the three major epicardial coronary arteries, applying the atherometric system and classifying the atherosclerotic lesions into adipose stria, fibrous plate and grave plate.Results:
the association between atherosclerosis and osteoporosis exhibited specific features for each sex, with a significant predominance of osteoporosis in men and osteopenia in women. After removing the effect of cigarette smoking, there was a change in the differences between the sexes, with smokers of both sexes presenting a similar BMD and a similar association between atherosclerosis and osteoporosis.Conclusions:
the influence of sex upon the association between atherosclerosis and osteoporosis was negligibleKey words
Full text:
1
Index:
LILACS
Main subject:
Coronary Artery Disease
/
Osteoporosis, Postmenopausal
Type of study:
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
Language:
Es
Journal:
Rev. cuba. invest. bioméd
Journal subject:
MEDICINA
Year:
2013
Type:
Article