Puerperal brain cryptococcoma in an HIV-negative woman successfully treated with fluconazole: a case report
Rev. Soc. Bras. Med. Trop
; 47(2): 254-256, Mar-Apr/2014. graf
Article
in En
| LILACS
| ID: lil-710359
Responsible library:
BR1.1
ABSTRACT
Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus flucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV-negative woman diagnosed with a large cryptococcoma in the immediate postpartum period. The lesion was not resected, and due to amphotericin B intolerance, she received an extended course of fluconazole monotherapy. There was no disease recurrence during the 4 years of follow-up. The abrupt onset of her symptoms following delivery suggests that she developed a postpartum immune reconstitution syndrome. This case also demonstrates that in specific situations fluconazole monotherapy can be attempted in immunocompetent patients with cryptococcoma.
Key words
Full text:
1
Index:
LILACS
Main subject:
Puerperal Infection
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Fluconazole
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Meningitis, Cryptococcal
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Antifungal Agents
Type of study:
Diagnostic_studies
Limits:
Adult
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Female
/
Humans
Language:
En
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
MEDICINA TROPICAL
Year:
2014
Type:
Article
/
Project document