Vitiligo - Part 2 - classification, histopathology and treatment
An. bras. dermatol
; 89(5): 784-790, Sep-Oct/2014. tab, graf
Article
in En
| LILACS
| ID: lil-720797
Responsible library:
BR1.1
ABSTRACT
In an unprecedented effort in the field of vitiligo, a global consensus resulted on a suggested new classification protocol for the disease. The main histopathological finding in vitiligo is the total absence of functioning melanocytes in the lesions, while the inflammatory cells most commonly found on the edges of the lesions are CD4+ and CD8+ T lymphocytes. Physical and pharmacological treatment strategies aim to control the autoimmune damage and stimulate melanocyte migration from the unaffected edges of lesions and the outer hair follicle root sheath to the affected skin; moreover, surgical treatments can be combined with topical and physical treatments.
Key words
Full text:
1
Index:
LILACS
Main subject:
Vitiligo
Type of study:
Guideline
Limits:
Female
/
Humans
/
Male
Language:
En
Journal:
An. bras. dermatol
Journal subject:
DERMATOLOGIA
Year:
2014
Type:
Article