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Isolated Schwannoma of the Olfactory Groove: A Case Report
Nascimento, Luiz Augusto; Settanni, Flávio Aurélio Parente; Góis Filho, José Franscisco de; Sanchez, Isabela Naria Dias; Cavalcante, Bruna Barros; Stávale, João Noberto.
  • Nascimento, Luiz Augusto; São Paulo. São Paulo. BR
  • Settanni, Flávio Aurélio Parente; São Paulo. São Paulo. BR
  • Góis Filho, José Franscisco de; São Paulo. São Paulo. BR
  • Sanchez, Isabela Naria Dias; São Paulo. São Paulo. BR
  • Cavalcante, Bruna Barros; São Paulo. São Paulo. BR
  • Stávale, João Noberto; São Paulo. São Paulo. BR
Int. arch. otorhinolaryngol. (Impr.) ; 19(1): 93-95, Jan-Mar/2015. graf
Article in English | LILACS | ID: lil-741535
ABSTRACT
Introduction Schwannoma of the olfactory groove is an extremely rare tumor that can share a differential diagnosis with meningioma or neuroblastoma. Objectives The authors present a case of giant schwannoma involving the anterior cranial fossa and ethmoid sinuses. Case Report The patient presented with a 30-month history of left nasal obstruction, anosmia, and sporadic ipsilateral bleeding. Computed tomography of the paranasal sinuses revealed expansive lesion on the left nasal cavity extending to nasopharynx up to ethmoid and sphenoid sinuses bilaterally with intraorbital and parasellar extension to the skull base. Magnetic resonance imaging scan confirmed the expansive tumor without dural penetration. Biopsy revealed no evidence of malignancy and probable neural cell. Bifrontal craniotomy was performed combined with lateral rhinotomy (Weber-Ferguson approach), and the lesion was totally removed. The tumor measured 8.0 4.3 3.7 cm and microscopically appeared as a schwannoma composed of interwoven bundles of elongated cells (Antoni A regions)mixed with less cellular regions (Antoni B). Immunohistochemical study stained intensively for vimentin and S-100. Conclusion Schwannomas of the olfactory groove are extremely rare, and the findings of origin of this tumor is still uncertain but recent studies point most probably to the meningeal branches of trigeminal nerve or anterior ethmoidal nerves. .
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Full text: Available Index: LILACS (Americas) Main subject: Cell Membrane Permeability / Mechanotransduction, Cellular / Hair Cells, Auditory / Ion Channels Limits: Animals Language: English Journal: Int. arch. otorhinolaryngol. (Impr.) Journal subject: Otolaryngology Year: 2015 Type: Article Affiliation country: Brazil Institution/Affiliation country: São Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Cell Membrane Permeability / Mechanotransduction, Cellular / Hair Cells, Auditory / Ion Channels Limits: Animals Language: English Journal: Int. arch. otorhinolaryngol. (Impr.) Journal subject: Otolaryngology Year: 2015 Type: Article Affiliation country: Brazil Institution/Affiliation country: São Paulo/BR