Biofilm production by multiresistant Corynebacterium striatum associated with nosocomial outbreak
Mem. Inst. Oswaldo Cruz
; 110(2): 242-248, 04/2015. tab, graf
Article
in En
| LILACS
| ID: lil-744474
Responsible library:
BR1.1
ABSTRACT
Corynebacterium striatum is a potentially pathogenic microorganism that causes nosocomial outbreaks. However, little is known about its virulence factors that may contribute to healthcare-associated infections (HAIs). We investigated the biofilm production on abiotic surfaces of multidrug-resistant (MDR) and multidrug-susceptible (MDS) strains of C. striatum of pulsed-field gel electrophoresis types I-MDR, II-MDR, III-MDS and IV-MDS isolated during a nosocomial outbreak in Rio de Janeiro, Brazil. The results showed that C. striatum was able to adhere to hydrophilic and hydrophobic abiotic surfaces. The C. striatum 1987/I-MDR strain, predominantly isolated from patients undergoing endotracheal intubation procedures, showed the greatest ability to adhere to all surfaces. C. striatum bound fibrinogen to its surface, which contributed to biofilm formation. Scanning electron microscopy showed the production of mature biofilms on polyurethane catheters by all pulsotypes. In conclusion, biofilm production may contribute to the establishment of HAIs caused by C. striatum.
Key words
Full text:
1
Index:
LILACS
Main subject:
Foot
/
Nursing Care
Type of study:
Risk_factors_studies
Limits:
Adult
/
Aged
/
Humans
Language:
En
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
MEDICINA TROPICAL
/
PARASITOLOGIA
Year:
2015
Type:
Article
/
Project document