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Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159
Park, Soon-Nang; Ahn, Sug-Joon; Kook, Joong-Ki.
Affiliation
  • Park, Soon-Nang; Chosun University. School of Dentistry. Korean Collection for Oral Microbiology and Department of Oral Biochemistry. Gwangju. KR
  • Ahn, Sug-Joon; Chosun University. School of Dentistry. Korean Collection for Oral Microbiology and Department of Oral Biochemistry. Gwangju. KR
  • Kook, Joong-Ki; Chosun University. School of Dentistry. Korean Collection for Oral Microbiology and Department of Oral Biochemistry. Gwangju. KR
Braz. j. microbiol ; 46(2): 613-617, Apr-Jun/2015. tab, graf
Article in En | LILACS | ID: lil-749716
Responsible library: BR1.1
ABSTRACT
In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans.
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Full text: 1 Index: LILACS Main subject: Oleanolic Acid / Streptococcus mutans / Triterpenes / Peptidoglycan / Biosynthetic Pathways / Anti-Bacterial Agents Language: En Journal: Braz. j. microbiol Journal subject: MICROBIOLOGIA Year: 2015 Type: Article / Project document

Full text: 1 Index: LILACS Main subject: Oleanolic Acid / Streptococcus mutans / Triterpenes / Peptidoglycan / Biosynthetic Pathways / Anti-Bacterial Agents Language: En Journal: Braz. j. microbiol Journal subject: MICROBIOLOGIA Year: 2015 Type: Article / Project document