The effects of aqueous extract of babassu (Orbignya phalerata) on the pleura and lung parenchyma in rats
Acta cir. bras
;
31(4): 243-249, Apr. 2016. tab
Article
in English
| LILACS
| ID: lil-781328
ABSTRACT
PURPOSE:
To evaluate macro and microscopically, changes following the use of the aqueous extract of babassu (Orbignya phalerata) in the lung parenchyma and pleura of rats.METHODS:
Sixty adult male rats with average weight of 350 g, were randomized into two groups of 30 animals (experimental and control) further divided into sub-groups of 10 to be sacrificed at 48 h, 72 h and 21 days. The substance was injected into the right pleura of the animals.RESULTS:
There was intense pleuropulmonary macroscopic reaction with statistically significant differences between groups respectively (p<0.05, p<0.02, p<0.03). Microscopically, no statistically significant difference was evident (p>0.05).CONCLUSION:
The aqueous extract of babassu (Orbignya phalerata) was found to be highly irritating to the pleura and lung of rats, evidenced macroscopically by numerous adhesions and inflammation while no major changes were evident microscopically.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Pleura
/
Plant Extracts
/
Pleurodesis
/
Arecaceae
/
Lung
Type of study:
Evaluation studies
/
Prognostic study
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
General Surgery
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2016
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal do Maranhão/BR
Similar
MEDLINE
...
LILACS
LIS