Random-start controlled ovarian stimulation for emergency fertility preservation in a patient with myelodysplastic syndrome: a case report
Braz. j. med. biol. res
;
49(6): e5227, 2016. tab
Article
in English
| LILACS
| ID: lil-781417
ABSTRACT
This study reports a case of a gonadotropin-releasing hormone agonist trigger in a young female with myelodysplastic syndrome (MDS) who underwent fertility preservation using random-start controlled ovarian stimulation. This method involves the stimulation of the ovary regardless of a patient's menstrual-cycle phase. A review of the related literature is also provided. A 17-year-old patient was diagnosed with MDS and required initiation of peripheral blood stem cell transplantation within a maximum of 3 weeks and was in the luteal phase of the menstrual cycle when the possibility of attempting preservation of fertility was presented to her. She opted for a random-start controlled ovarian stimulation with gonadotropins. With successful hemorrhagic prophylaxis, 17 oocytes were retrieved including 10 mature and 7 immature oocytes. Of the immature oocytes, 3 were successfully matured in vitro and a vitrification protocol was used to freeze the 13 mature oocytes.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Ovulation Induction
/
Myelodysplastic Syndromes
/
Fertility Preservation
Type of study:
Controlled clinical trial
/
Practice guideline
Limits:
Adolescent
/
Female
/
Humans
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
2016
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
Peking University People's Hospital/CN
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