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Retinal nerve fiber layer, ganglion cell complex, and choroidal thicknesses in migraine / Espessuras da camada de fibras nervosas retinianas, complexo de células ganglionares e coroide na enxaqueca
Colak, Hatice Nur; Kantarcı, Feride Aylin; Tatar, Mehmet Gurkan; Eryilmaz, Mehmet; Uslu, Hasim; Goker, Hasan; Yildirim, Aydin; Gurler, Bulent.
  • Colak, Hatice Nur; Fatih University Medical Faculty Hospital. Department of Ophthalmology. Istanbul. TR
  • Kantarcı, Feride Aylin; Fatih University Medical Faculty Hospital. Department of Ophthalmology. Istanbul. TR
  • Tatar, Mehmet Gurkan; Fatih University Medical Faculty Hospital. Department of Ophthalmology. Istanbul. TR
  • Eryilmaz, Mehmet; Fatih University Medical Faculty Hospital. Department of Ophthalmology. Istanbul. TR
  • Uslu, Hasim; Fatih University Medical Faculty Hospital. Department of Ophthalmology. Istanbul. TR
  • Goker, Hasan; Fatih University Medical Faculty Hospital. Department of Ophthalmology. Istanbul. TR
  • Yildirim, Aydin; Fatih University Medical Faculty Hospital. Department of Ophthalmology. Istanbul. TR
  • Gurler, Bulent; Fatih University Medical Faculty Hospital. Department of Ophthalmology. Istanbul. TR
Arq. bras. oftalmol ; 79(2): 78-81, Mar.-Apr. 2016. tab, graf
Article in English | LILACS | ID: lil-782804
ABSTRACT
ABSTRACT

Purpose:

To evaluate the thicknesses of the peripapillary retinal nerve fiber layer (RNFL), ganglion cell complex (GCL), and choroid layer using spectral domain optical coherence tomography (SD-OCT) for investigating the effects of vascular changes on the eye and optic nerve in patients who have migraine with aura.

Methods:

Forty-five patients who had migraine with aura (migraine group) and 45 healthy individuals (control group) were enrolled in the study. Age, gender, duration after migraine diagnosis, intraocular pressure, and axial length measurements were recorded in each case. RNFL, GCL, and choroid layer thicknesses were measured using SD-OCT in all participants.

Results:

The mean age was 36.1 ± 6.7 (20-45) years in the migraine group and 35.7 ± 8.6 (19-45) years in the control group. There was no significant difference in the RNFL thicknesses of the temporal and nasal quadrants (p >0.05). The RNFL thicknesses of the superior and inferior quadrants were significantly lower in the migraine group compared with those in the control group (p =0.001, p <0.01, respectively). Measurements for the superior and inferior GCL were not significantly different between the groups (p >0.05). Subfoveal, temporal, and nasal choroidal thickness measurements at 500 µm, 1000 µm, and 1500 µm were significantly lower in the migraine group than in the control group (p =0.001; p <0.01, respectively).

Conclusions:

Compared with the controls, the RNFL and choroid layer were determined to be thinner in patients who had chronic migraine with aura.
RESUMO
RESUMO

Objetivo:

Avaliar as espessuras de camada peripapilar de fibras nervosas retinianas (RNFL), complexo de células ganglionares (GCL) e da coroide utilizando a tomografia de coerência óptica de domínio espectral (SD-OCT), a fim de investigar os efeitos das alterações vasculares no olho e nervo óptico em pacientes que apresentam enxaqueca com aura.

Métodos:

Quarenta e cinco pacientes que apresentavam enxaqueca com aura (grupo enxaqueca) e 45 indivíduos saudáveis (grupo controle) foram incluídos no estudo. Idade, sexo, duração da enxaqueca, pressão intraocular e medidas de comprimento axial foram registrados em cada caso. Medidas da RNFL, GCL e espessuras da coroide foram obtidas com SD-OCT em todos os participantes.

Resultados:

A média da idade foi de 36,1 ± 6,7 (20-45) anos no grupo enxaqueca e 35,7 ± 8,6 (19-45) anos no grupo controle. Não houve diferença significativa em espessuras RNFL nos quadrantes temporal e nasal (p>0,05). A espessura da RNFL nos quadrantes superiores e inferiores foram significativamente menores no grupo de enxaqueca em comparação ao grupo controle (p=0,001; p<0,01). Medidas da GCL superior e inferior não mostraram diferença significativa entre os grupos (p>0,05). Espessuras subfoveais, temporais e nasais da coroide (CT) a 500 µm, 1000 µm e 1500 µm foram significativamente menores no grupo de enxaqueca em relação ao grupo controle (p=0,001; p<0,01).

Conclusões:

Comparados aos controles, as espessuras da RNFL e coroide foram mais finas em pacientes que apresentavam enxaqueca crônica com aura.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Retina / Retinal Ganglion Cells / Choroid / Migraine with Aura / Nerve Fibers Type of study: Observational study / Prevalence study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2016 Type: Article Affiliation country: Turkey Institution/Affiliation country: Fatih University Medical Faculty Hospital/TR

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Full text: Available Index: LILACS (Americas) Main subject: Retina / Retinal Ganglion Cells / Choroid / Migraine with Aura / Nerve Fibers Type of study: Observational study / Prevalence study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: Arq. bras. oftalmol Journal subject: Ophthalmology Year: 2016 Type: Article Affiliation country: Turkey Institution/Affiliation country: Fatih University Medical Faculty Hospital/TR