Modulatory effects of adrenergic agonists on testosterone secretion from rat dispersed testicular cells or Percoll-purified Leydig cells
Braz. j. med. biol. res
; 22(11): 1421-9, 1989. ilus
Article
in En
| LILACS
| ID: lil-83149
Responsible library:
BR26.1
RESUMO
Freshly dispersed testicular interstitial cells as well as Percoll-purified Leydig cells were studied in vitro in order to evaluate the effect of adrenergic agonists on testosterone (T) secretion. Epinephrine and phenylephrine did not change the rate of T release under basal conditions in freshly dispersed interstitial cells, but enhanced it during human chorionic gonadotropin (hCG) stimulation. Norepinephrine and clonidine had no effect on T secretion. In contrast, in Percoll-purified Leydig cells epinephrine increased T release both under basal and hCG-stimulated conditions. These data demonstrate that neurotransmitters may participate in T secretion from isolated Leydig cells
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Index:
LILACS
Main subject:
Phenylephrine
/
Testosterone
/
In Vitro Techniques
/
Epinephrine
/
Leydig Cells
Limits:
Animals
Language:
En
Journal:
Braz. j. med. biol. res
Journal subject:
BIOLOGIA
/
MEDICINA
Year:
1989
Type:
Article
/
Project document