Effect of fencamfamine on avoidance performances of rats
Braz. j. med. biol. res
;
24(3): 307-9, mar. 1991. tab
Article
in English
| LILACS
| ID: lil-99569
ABSTRACT
The effects of fencamfamine (1.0 and 5.0 mg/kg, ip single dose) on an inhibitory task were studied in rats (N=15 per group).Post-training treatment with fencamfamine (1.0 mg/kg) significantly increased avoidance latency from 23 ñ 3 to 146 ñ 28 and 170 ñ 33 s for training day 1 and day 7, respectively, indicating an enhacement of retention.However, retention was significantly reduced with a high dose of fencamfamine (5.0 mg/kg). These results demonstrate that fencamfamine caused a reproducible dose-related increase and reduction in avoidance latency
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Index:
LILACS (Americas)
Main subject:
Retention, Psychology
/
Avoidance Learning
/
Escape Reaction
/
Norbornanes
Limits:
Animals
Language:
English
Journal:
Braz. j. med. biol. res
Journal subject:
Biology
/
Medicine
Year:
1991
Type:
Article
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