Effect of extracts of Murraya koenigii leaves on the levels of blood glucose and plasma insulin in alloxan-induced diabetic rats.
Indian J Physiol Pharmacol
; 2004 Jul; 48(3): 348-52
Article
in En
| IMSEAR
| ID: sea-107225
ABSTRACT
The effect of daily oral administration of aqueous extract (600 mg/kg b.wt.) and methanol extract (200 mg/kg b.wt.) of Murraya koenigii Spreng leaves for a period of eight weeks was studied on blood glucose and plasma insulin level in alloxan-induced diabetic rats. Blood glucose levels of diabetic rats treated with aqueous and methanol extracts of Murraya koenigii Spreng showed significant reduction (P<0.05) as compared to diabetic control groups. Plasma insulin showed significantly high on 43rd and 58th days of treatment in aqueous and methanol extracts of Murraya koenigii treated groups. This suggests that the hypoglycemic effect may be mediated through stimulating insulin synthesis and/or secretion from the beta cells of pancreatic islets of Langerhans.
Full text:
1
Index:
IMSEAR
Main subject:
Rats
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Blood Glucose
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Female
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Male
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Plant Extracts
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Islets of Langerhans
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Rats, Sprague-Dawley
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Plant Leaves
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Murraya
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Diabetes Mellitus, Experimental
Language:
En
Journal:
Indian J Physiol Pharmacol
Year:
2004
Type:
Article