Effect of 'Arogyavardhini' against carbon tetrachloride induced hepatic damage in albino rats.
Indian J Physiol Pharmacol
; 1987 Jan-Mar; 31(1): 25-9
Article
in En
| IMSEAR
| ID: sea-108497
ABSTRACT
'Arogyavardhini'-an indigenous formulation was evaluated for its hepatoprotective activity in rats, using two models of carbon tetrachloride (CCl4) hepatic damage, one simulating vital hepatitis and the other simulating fatty change. The protective effect was assessed from serum aspartate transaminase (AST) and alkaline phosphatase levels and from histopathological changes in liver. The results revealed that 'Arogyavardhini' (5 mg/100g, PO daily) was effective in minimizing the changes in serum levels of AST and alkaline phosphatase induced by CCI. The protective effect was also evident on histopathological examination.
Full text:
1
Index:
IMSEAR
Main subject:
Aspartate Aminotransferases
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Rats
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Male
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Carbon Tetrachloride Poisoning
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Plant Extracts
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Drug Combinations
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Alkaline Phosphatase
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Fatty Liver
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Hepatitis, Viral, Animal
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Liver
Language:
En
Journal:
Indian J Physiol Pharmacol
Year:
1987
Type:
Article