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Reduced toxicity and enhanced antitumor efficacy of betacyclodextrin plumbagin inclusion complex in mice bearing Ehrlich ascites carcinoma.
Singh, U V; Udupa, N.
Indian J Physiol Pharmacol ; 1997 Apr; 41(2): 171-5
Article in En | IMSEAR | ID: sea-108776
ABSTRACT
Inclusion complex of plumbagin was prepared with betacyclodextrin employing neutralization method. The toxicity of the drug was reduced and the antitumor efficacy was enhanced on complexation with betacyclodextrin.
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Full text: 1 Index: IMSEAR Main subject: Female / Drug Carriers / Carcinogens / Carcinoma, Ehrlich Tumor / Analysis of Variance / Naphthoquinones / Cyclodextrins / Beta-Cyclodextrins / Dose-Response Relationship, Drug / Drug Synergism Language: En Journal: Indian J Physiol Pharmacol Year: 1997 Type: Article
Fulltext
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Full text: 1 Index: IMSEAR Main subject: Female / Drug Carriers / Carcinogens / Carcinoma, Ehrlich Tumor / Analysis of Variance / Naphthoquinones / Cyclodextrins / Beta-Cyclodextrins / Dose-Response Relationship, Drug / Drug Synergism Language: En Journal: Indian J Physiol Pharmacol Year: 1997 Type: Article