Suprasellar malignant mixed germ cell tumour presenting as craniopharyngioma.
Neurol India
; 2000 Dec; 48(4): 381-4
Article
in En
| IMSEAR
| ID: sea-121514
ABSTRACT
A 15 year old boy presented with diminution in vision of both eyes, diabetes insipidus and hypopituitarism. MRI was suggestive of a large suprasellar and retrosellar craniopharyngioma with stretching of the optic chiasma. Histopathological findings on the first surgical specimen were interpreted as a craniopharyngioma. He was reoperated on account of clinical deterioration and increase in tumour size. Histological examination this time revealed derivatives of all three germ cell lineages along with areas of embryonal carcinoma, and yolk sac tumour besides squamous cysts, establishing the diagnosis of malignant mixed germ cell tumour. Serum and CSF were strongly positive for alpha foetoproteins.
Full text:
1
Index:
IMSEAR
Main subject:
Optic Chiasm
/
Pituitary Neoplasms
/
Humans
/
Male
/
Magnetic Resonance Imaging
/
Alpha-Fetoproteins
/
Adolescent
/
Mixed Tumor, Malignant
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Germinoma
/
Craniopharyngioma
Type of study:
Diagnostic_studies
Language:
En
Journal:
Neurol India
Year:
2000
Type:
Article