jefA (Rv2459), a drug efflux gene in Mycobacterium tuberculosis confers resistance to isoniazid & ethambutol.

Gupta, Anuj Kumar; Reddy, Vineel P; Lavania, Mallika; Chauhan, D S; Venkatesan, K; Sharma, V D; Tyagi, A K; Katoch, V M

Gupta, Anuj Kumar; Reddy, Vineel P; Lavania, Mallika; Chauhan, D S; Venkatesan, K; Sharma, V D; Tyagi, A K; Katoch, V M.

Article in En | IMSEAR | ID: sea-135571

Subject(s)

Amino Acid Sequence; Bacterial Proteins/chemistry; Bacterial Proteins/genetics; Bacterial Proteins/physiology; Base Sequence; Cloning, Molecular; Cluster Analysis; Computational Biology; DNA Primers/genetics; Drug Resistance, Microbial/genetics; Ethambutol; Isoniazid; Membrane Transport Proteins/chemistry; Membrane Transport Proteins/genetics; Membrane Transport Proteins/physiology; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis/genetics; Open Reading Frames/genetics; Phylogeny; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA

Key words

Drug efflux; ethambutol; isoniazid; jefA; Mycobacterium tuberculosis

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Full text: 1 Index: IMSEAR Main subject: Membrane Transport Proteins / Phylogeny / Bacterial Proteins / Drug Resistance, Microbial / Molecular Sequence Data / Base Sequence / Microbial Sensitivity Tests / Models, Molecular / Cluster Analysis / Open Reading Frames Type of study: Prognostic_studies Language: En Year: 2010 Type: Article

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