Evaluation of the relative efficacy of copolymerized polylactic-polyglycolic acids alone and in conjunction with polyglactin 910 membrane in the treatment of human periodontal infrabony defects: A clinical and radiological study.
Article
in English
| IMSEAR
| ID: sea-139957
ABSTRACT
Background:
Absorbable synthetic biopolymers have been used as bone filler in Periodontology, proving effective stimulants to bone regeneration.Aim:
Copolymerized polylactic and polyglycolic acid is used as a bone filler and polyglactin 910 as a guided tissue regeneration (GTR) membrane to achieve regeneration in periodontal infrabony defects. Materials andMethods:
Forty patients with two- or three-walled infrabony defects were selected and randomly divided into two groups. Group A included patients treated with polylactic-polyglycolic acids 5050 (Fisiograft® ,Ghimsa SPA,Via Fucini, Italy) alone and Group B included patients treated with polylactic-polyglycolic acids (PLA-PGA)5050 in conjunction with polyglactin acid 910 (Vicryl Mesh® Johnson&Johnson , U.S.A ). Evaluation of clinical parameters probing depth and attachment level and radiographs was done preoperatively and 12 and 24 weeks postoperatively.Results:
Both the groups showed statistically significant mean reduction in probing depth and gain in clinical attachment level and linear bone fill.Conclusions:
Within the limit of this study, both the treatment modalities are beneficial for the treatment of infrabony defects.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Periodontal Diseases
/
Polyglactin 910
/
Polyglycolic Acid
/
Biocompatible Materials
/
Bone Regeneration
/
Humans
/
Alveolar Bone Loss
/
Treatment Outcome
/
Guided Tissue Regeneration, Periodontal
/
Bone Substitutes
Language:
English
Year:
2011
Type:
Article
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